NPACE Cardiovascular Pharmacotherapeutics Update: Chronic Heart Failure and Hypertension

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The first part of the session will outline methods of titrating optimal therapy using the most appropriate pharmacologic agents for treating adults with reduced ejection fraction.

The second half of the session discusses the use of at least 6 classes of medications to treat hypertension (HTN) in adults, including general principles for dosing, titration, and monitoring for side effects over time.


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Written course material and evaluation MUST be accessed within 6 months after purchase.


After taking part in this educational activity, participants will be able to:

Chronic Heart Failure

  • Review the mainline pharmacological treatment for patients with heart failure with reduced ejection fraction (HFrEF).
  • Discuss the rationale to consider use of two new classes of medication for patients with reduced ejection fraction.
  • Discuss the challenges and barriers to up-titration of medications that are indicated for this patient population.
  • Discuss situations that would trigger a referral to a HF specialist.
  • Discuss importance of shared decision making, with patients with advanced HF, especially when considering new classes of medications.

Hypertension (HTN)

  • Review four primary classes of medications to treat essential hypertension in adults.
  • Consider circumstances to use a loop diuretic to treat HTN as opposed to a thiazide diuretic.
  • Discuss use of spironolactone in treatment of resistant hypertension, including starting dose, titration, and monitoring for side effects.
  • Outline circumstances for use of other pharmacologic options to treat HTN.
  • Review over the counter medications or other substances that interfere with effectiveness of antihypertensive medications.
  • Discuss reasonable time frames to be used to evaluate the effectiveness of pharmacologic agents.


2 hours

Each video is accessible twice within six months of purchase.


NPACE designates this educational activity for a maximum of 1.5 CNE credit(s), of which 1.5 is pharmacology credit. Participants should claim only credit commensurate with the extent of their participation in the activity.


February 2021; Reviewed February 2022


NPACE aims to provide up-to-date and accurate research and information in all of their programming. Given that so much information in medicine rapidly changes and is dynamic – we recognize that new research, advisements for practice and clinical guidelines can become available on a daily basis. Learners are advised to carefully consider the date of on-demand content and consult further sources of information prior to utilizing and applying the clinical information discussed in this session.


Program ID: 20CACHF

Provider Accreditation Statement

This program is provided by Nurse Practitioner Associates for Continuing Education (NPACE).

Nurse Practitioner Associates for Continuing Education (NPACE) is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

In addition to ANCC, NPACE is approved as a provider of continuing education in nursing by: the California Board of Registered Nursing, Provider Number CEP8720 and Florida CE Broker #50-1476.

NPACE, the Provider of awarding contact hours, is responsible for adherence to ANCC criteria.


This course is taught by Leslie L. Davis, PhD, RN, ANP-BC, FAANP, FACC, FAHA, FPCNA. Dr. Davis is an Associate Professor of Nursing at the University of North Carolina at Chapel Hill, School of Nursing, PhD Division as well as a part-time NP with the Cardiology Division at UNC. She is an AANP, ACC and AHA fellow. Leslie L. Davis has disclosed no relevant financial relationships.


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Minimum space required: Each video section may take up to 150 MB. Each audio section may take up to 90 MB. Requires iPhone versions 5 and above and iPad Air and Mini and above.

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